Synthesis and biological evaluation of some stilbene derivatives

A polarographic study of some stilbene derivatives of biological interest.

synthesis and characterization of some macrocyclic schiff bases

ماکروسیکلهای شیف باز از اهمیت زیادی در شیمی آلی و دارویی برخوردار می باشند. این ماکروسیکلها با دارابودن گروه های مناسب در مکانهای مناسب می توانند فلزاتی مثل مس، نیکل و ... را در حفره های خود به دام انداخته، کمپلکسهای پایدار تولید نمایند. در این پایان نامه ابتدا یک دی آلدئید آروماتیک از گلیسیرین تهیه می شود و در مرحله بعدی واکنش با دی آمینهای آروماتیک و یا آلیفاتیک در رقتهای بسیار زیاد منجر به ت...

Synthesis and Biological Evaluation of Some Novel Triazole Derivatives

A series of eighteen novel 2-[(4-amino-5pyridin-3-yl-4H-1,2,4-triazol-3-yl)thio]-N-(substituted phenyl) propanamides 3(a-i) and 2-[(4-amino-5-phenyl-4H-1,2,4-triazol-3-yl) thio]-N-(substituted phenyl) propanamides 5(a-i) were synthesized by reacting 4-amino-5-pyridin-3-yl-4H-1,2,4-triazole-3-thiol (2) and 4-amino-5-phenyl-4H1,2,4-triazole-3-thiol (4) with the respective 2-chloro-N-(substituted ...

Synthesis, Biological evaluation and Comparative Study of Some Cinnoline Derivatives

In medicinal chemistry nitrogen containing heterocycles are the most important compounds which show various biological activities. The cinnoline are nitrogenous derivatives and found to elicit many pharmacological actions like anti-hypertensive, antithrombotic, antihistamine, antileukemic, CNS activity, anti tumor, antibacterial and antisecretory activity. We planned to synthesis new series of ...

Synthesis and Biological Significance of Some 2-Azetidinone Derivatives

A new series of N-[2-(1H-1,2,3-benzotriazol-1-yl)ethyl]-4-(substitutedphenyl)-3-chloro-2-oxo-1-iminoazetidine, compounds 4(a-j) were synthesized. The structures of all the synthesized compounds were confirmed by chemical and spectral analyses such as IR, 1H NMR, 13C NMR and FAB-Mass. The compounds 4(a-j) were screened for their antibacterial, antifungal and antitubercular activities and gave ac...